KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
13.33
Human Site:
T384
Identified Species:
22.56
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
T384
R
H
L
E
A
I
L
T
K
I
S
L
K
N
N
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
T384
R
H
L
E
A
I
L
T
K
I
S
L
K
N
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
S384
R
H
L
E
A
I
L
S
N
I
S
L
K
N
N
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
I384
N
H
L
E
E
I
L
I
K
I
P
L
T
N
N
Rat
Rattus norvegicus
NP_001101888
2143
241191
T384
K
H
L
E
A
I
L
T
K
I
P
L
T
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
Q384
K
H
L
E
G
I
L
Q
S
I
P
L
E
K
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
L386
L
Q
S
V
F
Q
N
L
Q
L
S
S
N
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
A385
V
P
M
P
K
P
T
A
Q
Q
L
I
N
C
F
Honey Bee
Apis mellifera
XP_393800
2028
231830
G381
R
I
K
L
D
D
I
G
V
D
T
I
L
W
N
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
E73
F
A
N
D
L
F
S
E
E
R
V
D
F
V
R
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
G58
N
G
L
Q
E
L
Q
G
I
D
P
R
F
H
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
V383
T
V
P
V
S
N
L
V
D
H
L
I
S
K
V
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
Y192
D
M
D
F
L
K
L
Y
T
S
Y
L
D
Q
C
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
L211
Y
Q
M
E
Y
P
G
L
I
S
F
W
G
G
V
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
100
N.A.
86.6
N.A.
66.6
80
N.A.
N.A.
46.6
N.A.
6.6
N.A.
0
13.3
0
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
66.6
86.6
N.A.
N.A.
66.6
N.A.
20
N.A.
20
33.3
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
29
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% C
% Asp:
8
0
8
8
8
8
0
0
8
15
0
8
8
0
15
% D
% Glu:
0
0
0
50
15
0
0
8
8
0
0
0
8
0
8
% E
% Phe:
8
0
0
8
8
8
0
0
0
0
8
0
15
0
8
% F
% Gly:
0
8
0
0
8
0
8
15
0
0
0
0
8
8
0
% G
% His:
0
43
0
0
0
0
0
0
0
8
0
0
0
8
0
% H
% Ile:
0
8
0
0
0
43
8
8
15
43
0
22
0
0
0
% I
% Lys:
15
0
8
0
8
8
0
0
29
0
0
0
22
15
0
% K
% Leu:
8
0
50
8
15
8
58
15
0
8
15
50
8
8
0
% L
% Met:
0
8
15
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
8
0
0
8
8
0
8
0
0
0
15
36
43
% N
% Pro:
0
8
8
8
0
15
0
0
0
0
29
0
0
0
0
% P
% Gln:
0
15
0
8
0
8
8
8
15
8
0
0
0
8
0
% Q
% Arg:
29
0
0
0
0
0
0
0
0
8
0
8
0
0
8
% R
% Ser:
0
0
8
0
8
0
8
8
8
15
29
8
8
0
0
% S
% Thr:
8
0
0
0
0
0
8
22
8
0
8
0
15
0
0
% T
% Val:
8
8
0
15
0
0
0
8
8
0
8
0
0
8
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% W
% Tyr:
8
0
0
0
8
0
0
8
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _